Уважаемые коллеги, доброго времени суток! Представляем вам американское научное издание Experimental Eye Research. Журнал имеет второй квартиль, издается в Academic Press Inc., его SJR за 2022 г. равен 0,933, импакт-фактор 3,4, печатный ISSN - 0014-4835, электронный 1096-0007, предметные области - Сенсорные системы, Клеточная и молекулярная неврология, Офтальмология. Вот так выглядит обложка:
Редактором является Стивен Флислер, контактные данные - fliesler@buffalo.edu.
Основной целью журнала является публикация оригинальных научных работ по всем аспектам экспериментальной биологии глаза и глазных тканей, которые направлены на определение механизмов нормальной функции и/или заболевания. Наиболее приветствуются исследования тканей глаза, охватывающие такие дисциплины, как клеточная биология, биология развития, генетика, молекулярная биология, физиология, биохимия, биофизика, иммунология или микробиология. Рукописи, которые носят чисто клинический характер или относятся к хирургической области офтальмологии, не подходят для представления и в случае получения будут возвращены без рецензирования.
Адрес издания - https://www.sciencedirect.com/journal/experimental-eye-research
Пример статьи, название - Porcine models of choroidal neovascularization: A systematic review. Заголовок (Abstract) - Animal models of choroidal neovascularization (CNV) are extensively used in translational studies of CNV formation and to evaluate angiostatic treatment strategies. However, the current paucity of large animal models compared with rodent models constitutes a knowledge gap regarding the clinical translation of findings. Ocular anatomical and physiological similarities to humans suggest the pig as a relevant model animal. Thus, a systematic survey of porcine CNV models was performed to identify pertinent model parameters and suggest avenues for model standardization and optimization.
A systematic search was performed in PubMed and EMBASE on November 28, 2022 for porcine models of CNV. Following inclusion by two investigators, data from the articles were extracted according to a predefined protocol. A total of 14 articles, representing 19 independent porcine CNV models were included.
The included models were almost equally divided between laser-induced (53%) and surgically-induced (47%) models. Different specified breeds of domestic pigs (71%) were most commonly used in the studies. All studies used normal animals. Female pigs were reported used in 43% of the studies, while 43% did not report on sex of the animals. Younger pigs were typically used. The surgical models reported consistent CNV induction following mechanical Bruch's membrane rupture. The laser models used variants of the infrared diode laser (40%) or the frequency-doubled Nd:YAG laser (50%). Both lasers enabled successful CNV induction with reported induction rates ranging from 60 to 100%. Collateral damage to the neuroretina was reported for the infrared diode laser. CNV evaluation varied across studies with fluorescein angiography (50%) as the most used in vivo method and retinal sections (71%) as the most used ex vivo method. In interventional studies, quantification of lesions was in general performed between 7 and 14 days.
The field of porcine CNV models is relatively small and heterogeneous and almost equally divided between surgically-induced and laser-induced models. Both methods have allowed successful modeling of CNV formation with induction rates comparable to those of non-human primates. However, the field would benefit from standardization of model parameters and reporting. This includes laser parameters and validation of CNV formation as well as methods of CNV evaluation and statistical analysis.
Keywords: Animal model; Porcine; Pig; Choroidal neovascularization; Neovascular age-related macular degeneration
