This disease makes it difficult to conduct sexual activity, leads to sexual insolvency, severe depression and even family breakdown. Clinically, the pathology is manifested by the curvature of the penis. Peyronie's disease was first described in 1743 by the court surgeon Louis XV. However, to date, the etiology and pathogenesis of this disease remain insufficiently studied.
Peyronie's disease or fibroplastic induration of the penis, to put it in incomprehensible words. This is focal fibrosis of the protein membrane of the penis, leading to a curvature of the penis during erection in the direction where the protein membrane is not broken. The disease is among the rare ones, although the incidence of patients has increased somewhat in recent years. The prevalence of this disease is 388 people per 100,000 population or 2-3% in the male population.
The greatest number of cases of this disease occurs at the age of 50-60 years, although it can also occur in young people, and at least 25% of these patients suffer from erectile dysfunction. The incidence of fibroplastic penile induration increases with age.
Treatment of Peyronie's disease is indicated in the first period of the disease before the onset of plaque calcification at an angle of curvature of the penis less than 30-45 degrees. Surgical treatment is performed with a pronounced (more than 45 degrees) curvature of the penis, preventing sexual intercourse. Plication methods are used, plaque excision with simultaneous penile phalloendoprosthetics, various types of plastic.
Conservative treatment includes the use of anti-inflammatory, antiviral, hormonal drugs, calcium channel blockers (verapamil). It is recommended to use various physiotherapeutic methods of treatment: laser magnetic therapy, ultrasound, percutaneous electrophoresis with verapamil, close-focus radiotherapy, shock wave therapy.
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