Уважаемые коллеги, доброго времени суток! Представляем вам нидерландское научное издание Journal of Cystic Fibrosis. Журнал имеет первый квартиль, издается в Elsevier, его SJR за 2022 г. равен 1,747, пятилетний импакт-фактор 5,537, печатный ISSN - 1569-1993, электронный - 1873-5010, предметные области - Педиатрия, перинатология и охрана здоровья детей, Легочная и респираторная медицина. Вот так выглядит обложка:
Редактором является Патрик Флуме, контактные данные - flumepa@musc.edu, BellS@health.qld.gov.au.
Это официальный журнал Европейского общества по муковисцидозу. Он посвящен популяризации исследований и лечения муковисцидоза. С этой целью журнал публикует оригинальные научные статьи, передовицы, клинические случаи, краткие сообщения и другую информацию, имеющую отношение к муковисцидозу. Журнал также публикует новости и статьи, касающиеся деятельности и политики ECFS, а также других обществ, связанных с ECFS.
Адрес издания - https://www.cysticfibrosisjournal.com/
Пример статьи, название - Eradication of Nontuberculous Mycobacteria in People with Cystic Fibrosis Treated with Elexacaftor/Tezacaftor/Ivacaftor: A Multicenter Cohort Study. Заголовок (Abstract)
Background
The prevalence of nontuberculous mycobacteria (NTM) infections is rising in people with cystic fibrosis (pwCF). NTM infection, especially infection with Mycobacterium abscessus complex (MABC), is commonly associated with severe lung deterioration. The current treatment modalities, including multiple intravenous antibiotics, frequently fail to achieve airway eradication. Although treatment with elexacaftor/tezacaftor/ivacaftor (ETI) has been shown to modulate the lung microbiome, data regarding its role in eradicating NTM in pwCF is lacking. Our aim was to evaluate the impact of ETI on the rate of NTM eradication in pwCF.
Methods
This retrospective multicenter cohort study included pwCF from five CF centers in Israel. PwCF aged older than 6 who had at least one positive NTM airway culture in the past two years and were treated with ETI for at least one year were included. The annual NTM and bacterial isolations, pulmonary function tests, and body mass index were analyzed before and after ETI treatment.
Results
Fifteen pwCF were included (median age 20.9 years, 73.3% females, 80% pancreatic insufficient). In nine patients (66%) NTM isolations were eradicated following treatment with ETI. Seven of them had MABC. The median time between the first NTM isolation and treatment with ETI was 2.71 years (0.27-10.35 years). Eradication of NTM was associated with improved pulmonary function tests (p<0.05).
Conclusions
For the first time, we report successful eradication of NTM, including MABC, following treatment with ETI in pwCF. Additional studies are needed to assess whether treatment with ETI can result in the long-term eradication of NTM.
Graphical abstract
Keywords: Cystic fibrosis; nontuberculous mycobacteria; Mycobacterium abscessus subsp. abscessus; elexacaftor/tezacaftor/ivacaftor; Trikafta; Mycobacterium abscessus complex