To diagnose erectile dysfunction, determine their possible causes and select adequate treatment, it is necessary to collect a complete medical history and conduct a thorough physical examination. Treatments buy viagra australia over the counter for erectile dysfunction should be used with caution in patients with an anatomical deformity of the penis (angulation, cavernous fibrosis, Peyronie's disease), or in patients with risk factors for developing priapism (sickle cell anemia, multiple myeloma, leukemia).
Drugs intended for the treatment of erectile dysfunction should not be prescribed to men for whom sexual activity is undesirable buy viagra australia over the counter.
VIAGRA is a drug for the treatment of erectile dysfunction - erectile dysfunction. Acts on the natural mechanisms of erection. It is used in men suffering from erectile dysfunction of various origins (vascular, nervous disorders of erection).
Sildenafil is a potent and selective inhibitor of cGMP-specific phosphodiesterase type 5 (PDE5).
The physiological mechanism of penile erection involves the release of nitric oxide (NO) in the cavernous body during sexual stimulation.
Nitric oxide activates the enzyme guanylate cyclase, which leads to an increase in the level of cyclic guanosine monophosphate (cGMP), relaxation of the smooth muscles of the cavernous body and increased blood flow in the penis buy viagra australia over the counter.
Sildenafil does not have a direct relaxing effect on the isolated human corpus cavernosum, but actively enhances the relaxing effect of NO on this tissue by inhibiting PDE5, which is responsible for the breakdown of cGMP in the corpus cavernosum.
During sexual arousal, the local release of NO under the influence of sildenafil leads to inhibition of PDE5 and an increase in the level of cGMP in the cavernous body, resulting in smooth muscle relaxation and increased blood flow in the cavernous body order viagra australia over the counter.
A prerequisite for the effectiveness of sildenafil is sexual stimulation.
Indications
Treatment of erectile dysfunction characterized by an inability to achieve or maintain an erection of the penis sufficient for satisfactory intercourse viagra australia over the counter.
Viagra is effective only in the presence of sexual stimulation.
Contraindications
- Hypersensitivity to any component of the drug.
- Use in patients receiving constantly or intermittently nitric oxide donators, organic nitrates or nitrites in any form.
- Age up to 18 years.
- Not intended for use in women.
With caution: anatomical deformity of the penis buy viagra australia over the counter online (including angulation, cavernous fibrosis or Peyronne's disease), diseases predisposing to the development of priapism (such as sickle cell anemia, multiple myeloma, leukemia, thrombocythemia), diseases accompanied by bleeding, exacerbation of peptic ulcer disease, hereditary retinitis pigmentosa, heart failure, unstable angina, previous myocardial infarction, stroke or life-threatening arrhythmias in the last 6 months, arterial hypertension (BP> 170/100 mm Hg) or hypotension (BP < 90/50 mm Hg). Art.).
Side effects
Adverse events are usually transient and mild or moderate. The frequency of adverse events increases with increasing dose.
On the part of the body as a whole: asthenia, pain, abdominal pain, back pain, infection, flu-like syndrome buy viagra australia over the counter online.
From the side of the cardiovascular system: vasodilation (a side effect reported in clinical studies).
From the digestive system: diarrhea, nausea.
From the musculoskeletal system: joint pain, muscle pain.
From the side of the central nervous system and peripheral nervous system: dizziness (a side effect recorded in clinical studies), increased muscle tone, insomnia.
On the part of the respiratory system: nasal congestion, pharyngitis, rhinitis (a side effect recorded in clinical studies), sinusitis, respiratory tract infections, impaired respiratory function order viagra australia over the counter.
Dermatological reactions: rash.
On the part of the senses: vision changes: mild and transient, mainly a change in the color of objects, as well as increased perception of light and blurred vision (a side effect recorded in clinical studies), conjunctivitis.
From the urinary system: urinary tract infections.
From the reproductive system: dysfunction of the prostate gland.
When using the drug in doses exceeding the recommended, side effects were similar to those noted above, but usually occurred more often.
Listed below are the adverse events reported during post-marketing use.
From the side of the cardiovascular system: arterial hypotension, fainting, tachycardia, palpitations.
From the digestive system: vomiting (a side effect recorded in clinical studies).
From the reproductive system: prolonged erection and / or priapism.
From the senses: pain in the eyes, redness of the eyes.
Other: allergic reactions.
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