Prednisone over the counter has a pronounced anti-inflammatory and anti-allergic effect, has anti-shock and immunosuppressive activity. It affects various types of metabolism: it increases the level of glucose in the blood, has a catabolic effect, promotes the redistribution of adipose tissue, can cause osteoporosis, causes retention of sodium and water ions in the body, and increases blood pressure. It affects the inflammatory process in the connective tissue and reduces the possibility of scar tissue formation where can i buy prednisone over the counter.
Prednisone is an inactive substance that, after absorption from the gastrointestinal tract, enters the liver and is converted into the active metabolite prednisolone. The binding of prednisolone to plasma proteins is 90%. Prednisolone further undergoes biotransformation in the liver, kidneys and bronchi to oxidized forms that form conjugates with sulfuric and glucuronic acids. It is excreted by the kidneys mainly unchanged can you buy prednisone over the counter.
Indications to use
Rheumatism, rheumatoid arthritis, dermatomyositis, periarteritis nodosa, scleroderma, ankylosing spondylitis. Bronchial asthma, allergic diseases. False croup in children. Addison's disease, acute adrenal insufficiency, adrenogenital syndrome. Hepatitis, hepatic coma, hypoglycemic conditions, lipoid nephrosis. Agranulocytosis, various forms of leukemia, lymphogranulomatosis, thrombocytopenic purpura, hemolytic anemia. Chorea. Pemphigus, eczema, itching, exfoliative dermatitis, psoriasis, pruritus, seborrheic dermatitis, lupus erythematosus, erythroderma, alopecia where can i buy prednisone over the counter.
Contraindications for use
Hypersensitivity to prednisone; peptic ulcer of the stomach and duodenum in the acute phase, osteoporosis, Itsenko-Cushing's disease, a tendency to thromboembolism can you buy prednisone over the counter , renal failure, severe arterial hypertension, systemic mycoses, viral infections, vaccination period, active form of tuberculosis, glaucoma, productive symptoms in mental illness.
special instructions
During treatment (especially long-term), it is necessary to observe an ophthalmologist, control blood pressure and water and electrolyte balance, as well as pictures of peripheral blood and blood glucose levels; in order to reduce side effects, you can prescribe anabolic steroids, antibiotics, and also increase the intake of potassium in the body (diet, potassium supplements) where can i buy prednisone over the counter.
When indicating a history of psoriasis, prednisone in high doses is prescribed under the strict supervision of a physician. In diabetes mellitus, it is prescribed only for absolute indications or to prevent suspected insulin resistance. For nonspecific infections, it is used with caution and subject to simultaneous chemotherapy or antibiotic therapy where can i buy prednisone over the counter. In latent forms of tuberculosis, prednisone can only be used in combination with anti-tuberculosis drugs.
In Addison's disease, simultaneous use with barbiturates should be avoided.
After discontinuation of treatment, withdrawal syndrome, adrenal insufficiency, as well as an exacerbation of the disease, for which prednisone was prescribed, may occur where can i buy prednisone over the counter.
Side effect
From the endocrine system: Itsenko-Cushing's syndrome, weight gain, hyperglycemia up to the development of steroid diabetes, depletion (up to atrophy) of the adrenal cortex, negative nitrogen balance.
On the part of the digestive system: increased acidity of gastric juice, ulcerogenic effect on the gastrointestinal tract.
From the side of water and electrolyte balance: increased excretion of potassium, sodium retention in the body with the formation of edema.
From the side of the cardiovascular system: arterial hypertension.
From the musculoskeletal system: osteoporosis, aseptic necrosis of bones.
From the side of the central nervous system: mental disorders, steroid cataract, provocation of latent glaucoma where can i buy prednisone over the counter.
Others: decreased resistance to infections, delayed wound healing, increased blood clotting.