Pharmachologic effect
Stimulator of production of gonadotropins. Means with antiestrogenic and estrogenic activity. It has a non-steroidal structure, which is close to chlorotrianisen where can i buy clomid over the counter. It is believed that the action of clomiphene is due to specific binding to the estrogen receptors of the hypothalamus and pituitary gland, which increases the secretion of gonadotropic hormones from the pituitary gland. This in turn stimulates the maturation and endocrine activity of the follicle in the ovary, as well as the subsequent formation and stimulation of the function of the corpus luteum. In high doses, it inhibits the secretion of gonadotropins. It does not have gestagenic and androgenic activity where can i buy clomid over the counter.
Pharmacokinetics
When taken orally, it is well absorbed from the gastrointestinal tract. Metabolized in the liver. It undergoes enterohepatic recirculation. T1 / 2 is 5-7 days. It is excreted mainly with bile where can i buy clomid over the counter.
Active ingredient matches for Clomiphene
Anovulatory infertility (ovulation induction); amenorrhea (dysgonadotropic form), secondary amenorrhea, postcontraceptive amenorrhea; Stein-Leventhal syndrome (polycystic ovary syndrome); oligomenorrhea; galactorrhea (against the background of a pituitary tumor); Chiari-Frommel syndrome (syndrome of prolonged postpartum amenorrhea-galactorrhea); androgen deficiency; in men - oligospermia buy clomid without prescription.
Dosing regimen
The method of application and dosing regimen of a particular drug depends on its form of release and other factors where can i buy clomid over the counter. The optimal dosage regimen is determined by the doctor. Compliance of the dosage form of a particular drug with indications for use and dosing regimen should be strictly observed.
Taken inside. The dose and regimen of application is set individually, depending on the indications, treatment regimen and the effectiveness of therapy.
Side effect
From the digestive system: nausea, vomiting; rarely - gastralgia, flatulence, diarrhea, acute abdomen syndrome.
From the nervous system: headache, dizziness, drowsiness; rarely - a slowdown in the speed of mental and motor reactions, irritability, depression, insomnia.
On the part of the organ of vision: impaired perception of light, double vision, blurred contours, photophobia where can i buy clomid over the counter.
From the urinary system: increased urination; rarely - polyuria.
On the part of the reproductive system and mammary glands: compaction of the mammary glands, pain in the lower abdomen, dysmenorrhea, pathological uterine bleeding, an increase in the size of the ovary (including cystic); rarely - vaginal dryness, menorrhagia buy clomid without prescription.
Allergic reactions: rarely - rash, urticaria, allergic dermatitis, vasomotor disorders.
Others: rarely - increased appetite, increase or decrease in body weight, alopecia, soreness in the mammary glands, flushing of blood to the face where can i buy clomid over the counter.
Contraindications for use
Hypersensitivity to clomiphene where can i buy clomid over the counter; hepatic and / or renal failure; pregnancy, lactation (breastfeeding); ovarian cyst (with the exception of polycystic ovary syndrome); tumor or hypofunction of the pituitary gland; dysfunction of the thyroid gland or adrenal glands; metrorrhagia of unknown etiology; long-term or recently developed visual impairment; neoplasms of the genital organs; endometriosis; ovarian insufficiency against the background of hyperprolactinemia buy clomid without prescription.