Metronidazole belongs to 5-nitroimidazoles and has a wide spectrum of activity against anaerobic microorganisms Peptostreptococcus species, Clostridium spp., Bacterioides spp., Fusobacterium spp., Veillonella spp., Prevotella (Prevotella bivia, Prevotella buccae, Prevotella disiens) where can i buy metronidazole over the counter.
Suppresses the development of protozoa - Trichomonas vaginalis, Giardia intestinalis (Lamblia intestinalis), Entamoeba histolytica.
The mechanism of action is the biochemical reduction of the 5-nitro group of metronidazole by intracellular transport proteins of anaerobic microorganisms and protozoa where can i buy metronidazole over the counter.
The reduced 5-nitro group of can you buy metronidazole over the counter interacts with the deoxyribonucleic acid of cells, inhibiting the synthesis of their nucleic acids, which leads to the death of microorganisms.
Indications
Trichomonas vaginitis and urethritis in women, Trichomonas urethritis in men, giardiasis, amoebic dysentery; anaerobic infections caused by microorganisms sensitive to the drug. Combination therapy for severe mixed aerobic-anaerobic infections. Prevention of anaerobic infection during surgical interventions (especially on the abdominal organs, urinary tract).
In combination with amoxicillin: chronic gastritis in the acute phase, peptic ulcer of the stomach and duodenum in the acute phase, associated with Helicobacter pylori where can i buy metronidazole over the counter.
Contraindications
Hypersensitivity to any of the components of the drug and imidazoles;
organic lesions of the central nervous system (including epilepsy);
pregnancy and lactation period;
blood diseases, leukopenia (including history);
children's age up to 3 years (for this dosage form).
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Side effects
Allergic reactions: urticaria, skin rash.
Local reactions: burning sensation or irritation of the penis in the sexual partner, burning sensation or frequent urination, vulvitis (itching, burning pain or hyperemia of the mucous membrane in the vulva). After discontinuation of the drug, the development of vaginal candidiasis is possible can you buy metronidazole over the counter.
Systemic reactions: possible changes in taste sensations, including a "metallic" taste, dizziness, headache, dry mouth, nausea, vomiting, loss of appetite, crampy pain in the abdominal cavity, constipation or diarrhea, staining of urine in a dark color, leukopenia or leukocytosis buy flagyl over the counter.
Special Instructions
During the treatment period, ethanol is contraindicated (possible development of a disulfiram-like reaction: spastic abdominal pain, nausea, vomiting, headache, sudden rush of blood to the face) where can i buy metronidazole over the counter.
In combination with amoxicillin, it is not recommended for use in patients under 18 years of age.
With prolonged therapy, it is necessary to control the blood picture. With leukopenia, the possibility of continuing treatment depends on the risk of developing an infectious process.
The appearance of ataxia, dizziness, and any other deterioration in the neurological status of patients requires discontinuation of treatment.
May immobilize treponema and lead to a false positive Nelson test.
Colors urine dark.
In the treatment of trichomonas vaginitis in women and trichomonas urethritis in men, it is necessary to refrain from sexual activity. Mandatory simultaneous treatment of sexual partners. Treatment does not stop during menstruation. After therapy for trichomoniasis, control tests should be carried out for three regular cycles before and after menstruation.
After treatment of giardiasis, if symptoms persist, perform 3 stool tests at intervals of several days after 3-4 weeks (in some successfully treated patients, lactose intolerance caused by invasion may persist for several weeks or months, resembling the symptoms of giardiasis) can you buy metronidazole over the counter.
During the treatment period, it is recommended to stop breastfeeding.