Can you buy amoxicillin over the counter

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Amoxicillin is a broad-spectrum antibacterial bactericidal acid-resistant agent from the group of semi-synthetic penicillins can you buy amoxicillin over the counter.
Inhibits transpeptidase, disrupts the synthesis of peptidoglycan (supporting protein of the cell wall) during division and growth, causes bacterial lysis.

Due to the breadth of the spectrum of action, the drug is active against both gram-positive and gram-negative microorganisms. Clinically significant Gram-negative amoxicillin-susceptible organisms include Escherichia coli, Proteus mirabilis, Salmonella, Shigella, Campylobacter, Haemophilus influenzae, Bordetella pertussis, Leptospira, Chlamydia.

In addition, amoxicillin is active against all microorganisms sensitive to penicillin G, for example, group A, B, C, G, H, I, M streptococci, Streptococcus pneumoniae, staphylococci and Neisseria spp., not producing penicillinase, Erysipelothrix rhysiopathiae, Corynebacterium , Bacillus anthracis, Actinomycetes, Streptobacilli, Spirillium minus where can i buy amoxicillin over the counter, Pastereulla multocida, Listeria, Spirochaeta (Leptospira, Treponema, Borrelia) and others, as well as various anaerobic microorganisms (including peptococci, peptostreptococci, clostridia and fusobacteria) can you buy amoxicillin over the counter.

Absorption - fast, high (93%), food intake does not affect absorption, is not destroyed in the acidic environment of the stomach. When taken orally at a dose of 125 and 250 mg, the maximum concentration is 1.5-3 mcg / ml and 3.5-5 mcg / ml, respectively. The action develops 15-30 minutes after application and lasts 8 hours where can i buy amoxicillin over the counter.
The time to reach the maximum concentration after oral administration is 1-2 hours. It has a large volume of distribution - high concentrations are found in plasma, sputum, bronchial secretions (in purulent bronchial secretions, distribution is weak), pleural and peritoneal fluid, urine, contents of skin blisters, lung tissue , intestinal mucosa, female genital organs can you buy amoxicillin over the counter, prostate gland, middle ear fluid, bone, adipose tissue, gallbladder (with normal liver function), fetal tissues where can i buy amoxicillin over the counter.

When the dose is increased by 2 times, the concentration also increases by 2 times. The concentration in bile exceeds the concentration in plasma by 2-4 times. In the amniotic fluid and vessels of the umbilical cord, the concentration of amoxicillin is 25-30% of the level in the plasma of a pregnant woman. Poorly penetrates the blood-brain barrier, with inflammation of the meninges (meningitis), the concentration in the cerebrospinal fluid is about 20%. Communication with plasma proteins - 17%.

Partially metabolized where can i buy amoxicillin over the counter to form inactive metabolites. The half-life is 1-1.5 hours.

It is excreted by 50-70% by the kidneys unchanged by tubular excretion (80%) and glomerular filtration (20%), by the liver - 10-20%. A small amount is excreted in breast milk. In case of impaired renal function (creatinine clearance less than or equal to 15 ml / min), the half-life increases to 8.5 hours. Amoxicillin is removed by hemodialysis can you buy amoxicillin over the counter.

Amoxicillin is indicated for infectious and inflammatory diseases caused by bacteria that are not resistant to the drug:

infectious diseases of the upper and lower respiratory tract and ENT organs (tonsillitis, acute otitis media, pharyngitis, bronchitis, pneumonia, lung abscess);
infectious diseases of the genitourinary system (urethritis, pyelonephritis, pyelitis, chronic bacterial prostatitis, epididymitis; cystitis, adnexitis, septic abortion, endometritis, etc.);
gastrointestinal infections: bacterial enteritis. Combination therapy may be required for infections caused by anaerobic microorganisms;
infectious and inflammatory diseases of the biliary tract (cholangitis, cholecystitis) can you buy amoxicillin over the counter;
eradication of Helicobacter pylori (in combination with proton pump inhibitors, clarithromycin or metronidazole);
skin and soft tissue infections;
leptospirosis, listeriosis, Lyme disease (borreliosis);
endocarditis (including prevention of endocarditis during dental procedures).