Messenger RNA (mRNA) based vaccine technology is emerging as one of the frontrunners among the technologies being evaluated to develop a vaccine for COVID-19, with eighteen candidates currently in development globally, according to GlobalData.
Keshalini Sabaratnam, Pharma Analyst at GlobalData, comments: “RNA vaccines are an innovative approach as they offer several advantages over conventional vaccines, particularly when responding to a pandemic threat. While conventional vaccines developed with an attenuated or inactivated disease-causing pathogen or using proteins made by the pathogen (antigens) require long production times and have limited production capacity, RNA vaccines work by introducing an mRNA sequence that encodes the disease-specific antigen to trigger the body’s immune system.
“A major advantage of RNA vaccines is that RNA can be produced rapidly and cheaply in the laboratory, offering the potential to scale up production to meet the demands of a pandemic. Other advantages include enhanced immunogenicity and better safety profile compared to classical and other types of vaccines, as has been proven in clinical trials.”
Over 150 COVID-19 vaccines are currently under development by biopharmaceutical companies and research organizations around the world. Nine of them are in clinical trials...
Full text at GMPnews.Net