Doctors, supporters of the hypothesis of autoimmune thyroiditis, inform patients about the irreversibility of changes in the thyroid gland. They proceed from the fact that the immune system for some obscure reason takes up arms against the body and, instead of its harmonizing effect, has a harmful effect, persistently killing the cells and follicles of the thyroid gland. Such experts believe that this process is unidirectional - in the direction of damage, and irrevocable - formed for the rest of life. Is it so?
It turns out that there are many facts that, on the one hand, deny the aggressiveness of the immune system in autoimmune thyroiditis, and on the other hand, demonstrate the recoverability of thyroid tissue.
Svetlana Melanich
Thank you very much for the detailed and competent explanation. Very unexpected information. ))
Are these judgments correct?
The source of a common medical error in looking at autoimmune thyroiditis is in the course of university training. While studying at institutes (universities, academies), doctors are taught a one-sided look at the immune system. They are only informed that immune cells are able to 1) recognize and then 2) damage and remove excess and harmful from the body. Subsequently, the doctors are “convinced” of taking advanced courses and learning from new journals and textbooks, and some, the most inquisitive, from modern monographs and theses. There, they also predominantly discover knowledge of the aggressive nature of the immune system in general and in autoimmune thyroiditis of the thyroid gland in particular.
In fact, the immune system has two common and at the same time oppositely directed possibilities. The immune system as a zealous owner not only 1) removes all unnecessary, unnecessary and harmful from the body, but at the same time 2) provides favorable conditions for the renewal (regeneration) of tissues. Most doctors do not know that the immune system is directly involved in the renewal of organs, their regeneration, whether it is autoimmune thyroiditis or any other disease. Consider how this happens.
The exhausted tissue of the thyroid gland (as well as any other organ), in which cells have suffered from excessive activity, is subjected to a more intense influence of the immune system. More immune cells rush into the gland, which produce more antibodies. With the help of direct (cellular) and mediated (antibody) action, the immune system removes dead, exhausted and defective thyroid cells from the gland, thereby creating conditions for subsequent recovery.
FILM. Scientific evidence of reversibility and recovery in AIT.
In place of the dead gland sites connective tissue is formed. It is wrong to consider as a structure that displaces the cells and follicles of the thyroid gland. This fabric is not only a patch on the site of the dead structures. It provides other tissues with nutrients, performs a protective function, and also prepares conditions for subsequent regeneration and directly contributes to it. Therefore, if during autoimmune thyroiditis, places with connective (fibrous) tissue and cells of the immune system are detected in the structure of the thyroid gland, these are not signs of auto-aggression. These are signs of biological repair. Connective tissue in autoimmune thyroiditis can both be formed and self-destructed. Self-disposal by the body of excess connective tissue has been scientifically confirmed and practically known. The formation and elimination of connective tissue occurs with the participation of the immune and nervous systems.
It is important!
Pay attention to the important fact: a small number of immune cells and antibodies (AT-TPO and AT-TG) are provided in a healthy gland. On the form of a blood test, you will find an indication that a small amount of antibodies is present in the "norm". What are they doing there? Does the immune system even terrorize the thyroid gland so imperceptibly even in healthy people? Is it really the beginnings of thyroid autoimmune thyroiditis ... in all people? Certainly not.
The fact is that even in a healthy thyroid gland, with its moderate stress, single cells and follicles die from exhaustion. The thyroid gland has to be constantly and gradually updated, which is due to regeneration - the birth of new cells and the formation of follicles from them. At the same time, a small number of cells of the immune system are constantly present in the gland tissue, which eliminate the dead structures using their cellular abilities and antibodies (AT-TPO, AT-TG, etc.). But this is not an autoimmune thyroiditis! When the load on the thyroid gland increases, the immune system is more actively involved in the process of thyroid gland repair, removing excess and promoting regeneration. More immune cells and antibodies appear. The degree of depletion of the gland affects the activity of the immune system, and, accordingly, the amount of antibodies (AT-TPO and AT-TG) in the blood. With prolonged adverse conditions in which the body is located, the thyroid gland is forced to overwork longer and longer. Thyroid cells die more. The immune system exerts its warning abilities longer, accumulating its cells in the gland tissue. But this is not an autoimmune thyroiditis of the thyroid gland - not inflammation! Why? Because not every immune activity is definitely inflammation.
In the case of the thyroid gland, it is the adaptive participation of the immune system in the depletion of the gland. This is not a protective effect of immunity in tissue damage, characteristic of inflammation.
N.I.Pirogov also drew attention to the fact that not every process should be considered inflammation. Leading experts of the past years wrote about this in the manuals at the beginning of the birth of the hypothesis of autoimmune thyroiditis (academicians I.V.Davydovsky, D.S.Sarkisov, V.V.Serov, etc.). But the fashionable idea that appeared after the 50s of the 20th century to attribute responsibility for the suffering of organs in the form of autoimmune inflammation to the immune system turned out to be so tempting that many generations of specialists rushed into its implementation. Rejecting the biological patterns (in fact - the laws of Nature), trying not to notice the contradictory facts and forgetting the main direction of treatment (to restore, not to maintain), the specialists created a big wobbly house of cards - the hypothesis of autoimmune thyroiditis.
Practicing doctors know that some patients have a sign of reversibility - a decrease in the number of antibodies in autoimmune thyroiditis. But do not draw any conclusions. Why does the immune system suddenly pacify its aggression? Are you tired? It turns out that the reduction of antibodies in autoimmune thyroiditis occurs with the improvement of the conditions in which the patient is. This often happens after a stay on vacation. It is the rest that relieves the overload from the thyroid gland. And since the cells of the gland are less depleted and destroyed, the immune system also has to strain less. This becomes noticeable by the number of antibodies.
Advocates of the hypothesis of this disease "identified" such a pathological condition as "postpartum autoimmune thyroiditis". The natural over-exertion of the thyroid gland during pregnancy and childbirth, in the absence of a sufficient number of compensatory forces in the gland, leads to a depletion of the gland and excessive adaptive participation of the immune system in a well-known scenario. But at the same time, a moderate lack of compensation in the postpartum period is conducive to recovery. The body rushes to restore the gland. And he succeeds in this, since the gland is only marginally depleted (it can only provide for a woman, but it is difficult for her to nourish with the hormones of two — the woman and the fetus). Doctors know and write in scientific journals about reversibility in such cases!
The reversibility of autoimmune thyroiditis is confirmed by scientific research. For example, this is reflected in the article http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630910/ , which we presented in the film in an accessible form (see above).
This is only a part of the facts and circumstances that clearly indicate the beneficial and not the harmful involvement of the immune system in overstretching the thyroid gland. Autoimmune thyroiditis is a fiction of modern medicine. Autoimmune disorders in the thyroid gland are reversible!
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Website "Clinic of the thyroid gland", of Dr. A.V. Ushakov: http://www.dr-md.ru