A large number of facts have confirmed that the father is related to the health of the fetus because the fetus has 1/2 of the gene from the father. Whether this 1/2 gene is normal is very important for the fetus. So what problems should the husband pay attention to before pregnancy?
- (1) Married men who are engaged in spraying pesticides, herbicides, etc., should avoid the wife's pregnancy for at least 70 days. Industrial chemicals such as heavy metal lead, pot, methotrexate, gossypol, and chloropropane can affect the process of sperm production. Therefore, the husband should be exposed to such chemicals as little as possible before the wife becomes pregnant.
- (2) Obese husband can't let his wife get pregnant during the weight loss process. Because more harmful chemicals are stored in the body of obese people, certain fat-soluble chemicals such as hexachlorocyclohexane, organochlorinated pesticides such as DDT, and carcinogenic chemicals, polychlorinated biphenyls, are stored in fat. Generally speaking, environmental pollutants deposited in adipose tissue have less toxic effects on humans, but in the process of rapid weight loss, the fat stored in the body will be quickly re-catabolized, and the poison accumulated in fat is also It is then released into the human blood, which in turn causes direct or indirect damage to the sperm.
- (3) Husbands should not abuse drugs, let alone use estrogen-containing skin care grease. Many chemical drugs, such as estrogen, reserpine, chlorpromazine, etc., will affect the viability of sperm and increase the number of abnormal sperm.
- (4) The husband should not be partial. The production of sperm requires high-quality protein, calcium, zinc and other minerals and trace elements, arginine, multivitamins and so on. If you have a partial eclipse and lack these nutrients in your diet, sperm production will be affected, or some low-quality sperm will be produced.
- (5) The husband must quit smoking and drinking. The damage to the sperm of the wine has long been familiar to people. Many harmful substances in the smoke will also kill the sperm. Stop drinking and smoking at least 3 months before conception.
- (6) The husband must maintain a good and stable mood. If you are often depressed, troubled, or tempered, it will cause cerebral cortical dysfunction, resulting in nervous system, endocrine function, testicular spermatogenesis and sexual function instability, affecting sperm production and quality. Speaking of genetic diseases 21-trisomy syndrome people will feel strange, but ask who has seen idiots? Many people can describe his or her typical characteristics: flat face, collapsed nose, wide eye distance, oblique outer corner of the eye, tongue and mouth, runny nose, short body, poor development, low muscle tone. This kind of person with special facial and severe mental retardation, commonly known as "soft idiot", is medically known as congenital syndrome, also known as 21-trisomy syndrome. This is the most common hereditary disease, chromosomal disease, with a prevalence of 1 in 600-1/1000 in newborns, accounting for 70% of neonatal chromosomal abnormalities. Mainly manifested as mental retardation, accompanied by severe heart disease and multiple deformities. Therefore, the birth of children with 21-trisomy syndrome not only imposes a heavy burden on families and individuals, but also has a negative impact on society. In particular, the prevalence of this genetic disease is much higher than the incidence rate, and there is no reliable and effective treatment. Once this mentally handicapped child grows to the childbearing age, it can produce sick children and form a vicious circle.
The Beijing Institute of Obstetrics and Gynecology New Hospital eugenics research center has been systematically screening and prenatal diagnosis for thousands of pregnant women since the opening of the outpatient clinic in late June.
Regarding the etiology of congenital 21-trisomy syndrome, Wang Shuyu, director of the center, said: "The cause of the disease is abnormal chromosome number. The patient has a chromosome 21 more than normal. 80% of the extra chromosomes are from the mother. 20% comes from the father. As the mother ages, the risk of morbidity increases.” Who needs to have a prenatal diagnosis of congenital 21-trisomy syndrome? Director Wang said: "Depending on the age and birth history of pregnant women, pregnant women over the age of 35 and women born with 21-trisomy must undergo prenatal diagnosis during pregnancy. They should be in the first trimester (8-10 weeks). And the second trimester (16-20 weeks) to amniocentesis in the obstetrics clinic, extracting amniotic fluid for karyotype analysis of villus and amniotic fluid cells, the result is positive for the child to do abortion, the result is negative for normal fetus and can continue pregnancy. ”
Because the prenatal diagnosis method is complicated and has some traumatic nature, it cannot be targeted at all pregnant women. Director Wang suggested that pregnant women under the age of 35 can do prenatal screening; pregnancy-related protein in the first trimester, alpha-fetoprotein, free estriol and chorionic gonadotropin in the second trimester, and suspicious people to do prenatal diagnosis. She also emphasized that prenatal screening is not a diagnosis, there is a range of false positives (screening for high-risk pregnancy, prenatal diagnosis is not a child), false negative (screening for low-risk pregnancy, if not for prenatal diagnosis) And the child is missed). Only after prenatal diagnosis can the final diagnosis be made.